An integrated model for enzyme catalysis emerges from studies of hydrogen tunneling
- 26 March 2009
- journal article
- Published by Elsevier in Chemical Physics Letters
- Vol. 471 (4-6) , 179-193
- https://doi.org/10.1016/j.cplett.2009.01.038
Abstract
No abstract availableKeywords
This publication has 74 references indexed in Scilit:
- Temperature dependence of protein motions in a thermophilic dihydrofolate reductase and its relationship to catalytic efficiencyProceedings of the National Academy of Sciences, 2010
- Experimental Evidence for Hydrogen Tunneling when the Isotopic Arrhenius Prefactor (AH/AD) is UnityJournal of the American Chemical Society, 2008
- Enzyme structure and dynamics affect hydrogen tunneling: The impact of a remote side chain (I553) in soybean lipoxygenase-1Proceedings of the National Academy of Sciences, 2008
- Dynamic personalities of proteinsNature, 2007
- Illuminating the mechanistic roles of enzyme conformational dynamicsProceedings of the National Academy of Sciences, 2007
- Coordinated effects of distal mutations on environmentally coupled tunneling in dihydrofolate reductaseProceedings of the National Academy of Sciences, 2006
- Linking protein structure and dynamics to catalysis: the role of hydrogen tunnellingPhilosophical Transactions Of The Royal Society B-Biological Sciences, 2006
- Impact of Protein Flexibility on Hydride-Transfer Parameters in Thermophilic and Psychrophilic Alcohol DehydrogenasesJournal of the American Chemical Society, 2004
- Is Hydrogen Tunneling Involved in AcylCoA Desaturase Reactions? The Case of a Δ9 Desaturase That Transforms (E)-11-Tetradecenoic Acid into (Z,E)-9,11-Tetradecadienoic AcidPublished by Wiley ,2000
- The magnitude of enzyme transition state analog binding constantsBiochemical and Biophysical Research Communications, 1974