Neutralization of a phlebotomus (sandfly) fever virus in baby hamster kidney (BHK21) tissue culture Introduction of a simple microculture for plaque reduction tests

Publisher Website
Google Scholar
Abstract
The Sicilian type of phlebotomus fever virus is capable of producing plaques in BHK21 cells under a carboxymethyl-cellulose overlay medium. Neutralization tests, comprising plaque reduction and plaque inhibition tests, are reported and their value for diagnosis as well as for field surveys is suggested. A simple andrapid microculture for virus and antibody titrations is described.