Toxic Drug Effects on the Cornea

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Abstract
The unique anatomy and physiology of the cornea is reviewed prior to a brief discussion on the six factors responsible for maintenance of corneal transparency. The toxicity of topically applied drugs is then described for the following classes of chemicals: anesthetics, glaucoma drugs, preservatives, antiseptics, antiinfective drugs (antibacterials, antivirals, antifungals, antihelminthics, and antimalarials), metal compounds, antiarthritic drugs, antiinflammatory agents, antineoplastic drugs, and drugs used for treatment of central nervous system disorders.