A New Radiolysis Mechanism for 2′-Deoxyadenosine in Aqueous Deaerated Solution

Publisher Website
Google Scholar
Abstract
The effect of ionizing radiation on 2''-deoxyadenosine in aqueous deaerated solution produced various products, among them: 9-(2-deoxy-.alpha.-D-erythro-pentopyranosyl)adenine, 9-(2-deoxy-.beta.-D-erythro-pentopyranosyl)adenine and 9-(2-deoxy-.alpha.-D-erythro-pentofuranosyl)adenine. These compounds may be formed by the opening of the C1''-O bond of the deoxyribose residue during the radiolysis producing a Schiff''s base-type intermediate and leading to rearrangement of the initial molecule into 4 .alpha.- and .beta.-pyranoic and furanoic forms.

This publication has 0 references indexed in Scilit: