Central Venous Catheter-Induced Endocarditis: Human Correlate of the Animal Experimental Model of Endocarditis

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Abstract
A case of right-sided endocarditis clearly associated with the presence of a right atrial catheter is presented, and the literature on septicemia and endocarditis associated with central venous and pulmonary artery catheterization is reviewed. In the majority of cases of catheter-associated endocarditis reported in the literature, diagnosis has been made at autopsy; echocardiographic diagnosis has been reported only recently. The case presented in this report represents the only case in this literature in which the lesion causing right-sided endocarditis has been identified by two-dimensional echocardiogram and confirmed by tissue diagnosis. The mechanism of direct traumatization of the endocardium by the catheter makes central venous catheter-induced endocarditis bear pathophysiologic similarity to the experimental model of endocarditis in animals.

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