Synthesis of 5,6‐dihydro‐4H‐pyrrolo[1,2‐a]thieno[2,3‐f][1,4]diazepines
- 1 June 1991
- journal article
- research article
- Published by Wiley in Journal of Heterocyclic Chemistry
- Vol. 28 (4) , 945-950
- https://doi.org/10.1002/jhet.5570280418
Abstract
The reduction of 1‐[3‐(thienyl‐2‐carbonitrile)]pyrrole, formed by condensation of 3‐aminothiophene‐2‐carbonitrile with 2,5‐dimethoxytetrahydrofuran, gave 1‐[3‐(thienyl‐2‐aminomethyl)]pyrrole. This compound was found to be a convenient intermediate for the preparation of 4‐aryl‐5,6‐dihydro‐4H‐pyrrolo[1,2‐a]thieno‐[2,3‐f][1,4]diazepines which was accomplished by two different synthetic routes.Keywords
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