Cervical screening in England and Wales: its effect has been underestimated
- 1 December 2000
- journal article
- research article
- Published by Wiley in Cytopathology
- Vol. 11 (6) , 471-479
- https://doi.org/10.1046/j.1365-2303.2000.00272.x
Abstract
Opinions about cervical screening in the UK tend to follow one of two negative lines of thought. The first is that cervical cancer is a rare disease, and too much time and effort are spent on screening. The second is that it has been relatively ineffective, since incidence of invasive carcinoma did not fall until the NHS Cervical Screening Programme (NHSCSP) was introduced in 1988, although it fell by 40% since then. This paper presents publicly available data to demonstrate that neither of these views is true. Registrations of invasive carcinoma of the uterine cervix and carcinoma in situ in England and Wales between 1971 and 1996 show that a substantially increased risk of disease in women born since 1940 has been reversed, almost certainly by greatly improved screening. Cervical carcinoma is now a rare disease because most cases are prevented before they become invasive, mostly by screening young women, aged 20–40, before the decade of life when symptomatic cervical carcinoma most frequently presents.Keywords
This publication has 17 references indexed in Scilit:
- Cervical screeningThe Lancet, 2000
- Double jeopardy for women in cervical screeningThe Lancet, 1999
- Cervical intraepithelial neoplasia grade III (CIN III) and invasive cervical carcinoma: the yawning gap revisited and the treatment of riskCytopathology, 1999
- Effect of screening on incidence of and mortality from cancer of cervix in England: evaluation based on routinely collected statisticsBMJ, 1999
- Evaluation of the ThinPrep Pap Test in Clinical PracticeActa Cytologica, 1998
- Invasive cervical cancer after conservative therapy for cervical intraepithelial neoplasiaThe Lancet, 1997
- The economics of screeningCytopathology, 1996
- Human papillomavirus testing in primary cervical screeningThe Lancet, 1995
- Detection rates for abnormal cervical smears: what are we screening for?The Lancet, 1995
- Natural History of Cervical Intraepithelial NeoplasiaInternational Journal of Gynecological Pathology, 1993