Gloss measurement on film coated tablets

Publisher Website
Google Scholar
Abstract
The gloss of film coated tablets has been assessed using a commercially available specular glossmeter modified to measure the specular reflectance of individual flat-faced, film-coated tablets. For all the pigmented film formulations studied, there was a decrease in gloss with increasing pigment concentration, the magnitude of the decrease being dependent on the pigment used. Film coatings prepared using an aqueous coating system had a much lower gloss reading than those prepared using an organic solvent coating system. Increasing the mean particle size of an inert filler particle resulted in a minimum gloss reading at intermediate particle sizes, while increasing the polymer concentration resulted in a significant decrease in gloss. In the latter case a power law equation was found to fit the data relating the percentage decrease in gloss with the percentage increase in roughness. The results are consistent with the known theories of specular reflectance and illustrate the potential of this rapid and simple technique in the optimization of film formulation and process variables during product development.

This publication has 5 references indexed in Scilit: