Theoretical temperature distributions for solenoidal‐type hyperthermia systems

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Abstract
One type of system proposed for producing hyperthermia for cancer therapy of deep-seated tumors consists of a cylindrical conducting coil (solenoid) in which the patient (or a limb of the patient) is placed. The current in the conducting coil creates an alternating magnetic field inside the patient, which induces eddy currents in the tissue. The eddy currents deposit power and hence produce heating. Steady-state temperature profiles are calculated analytically, assuming a homogeneous 1-dimensional model which includes blood perfusion. Numerical methods are used to calculate the temperature distributions as a function of time for this homogeneous model and to calculate the temperature profiles when there are radial variations in tissue parameters including blood flow. Based on these computer simulations, in most cases a solenoid-type hyperthermia system will not be able to provide deep-seated heating in the abdomen or thorax, but should be able to raise temperatures to therapeutic levels to about 6 cm depth in the abdomen and in the muscle layer in the thorax.
Funding Information
  • National Cancer Institute
  • National Institutes of Health (DHHS(CA 25394))
  • National Institutes of Health (DHHS(CA 19386))

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