EFFECT OF GLIBENCLAMIDE ON GLUCAGON AND INSULIN SECRETIONS STUDIED ON ISOLATED AND PERFUSED RAT PANCREAS

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  • 1 January 1975
    • journal article
    • research article
    • Vol. 169  (6) , 1568-1571
Abstract
Glibenclamide stimulates the insulin secretion by the isolated and perfused rat pancreas, but does not inhibit glucagon secretion when the perfusion liquid contains 1.5 g/l glucose. In the absence of glucose in the perfusion medium, glibenclamide stimulates both insulin and glucagon secretions.

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