Gestational Thrombocytopenia

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Abstract
It has been known for many years that the platelet-reactive autoantibodies responsible for platelet destruction in chronic idiopathic (autoimmune) thrombocytopenic purpura (ITP) can cross the placenta and cause thrombocytopenia in the fetus.1 The frequency and severity of this complication are not directly related to the severity of the disease in the mother and can even occur in infants born to women who have achieved normal platelet levels after a splenectomy. About half the infants born to women with active ITP or a history of the disease have subnormal platelet counts at birth. Usually this condition is mild, and the affected . . .