Hypoxia, angiotensin‐II, and norepinephrine mediated apoptosis is stimulus specific in canine failed cardiomyocytes: a role for p38 MAPK, Fas‐L and cyclin D1
Open Access
- 24 March 2003
- journal article
- research article
- Published by Wiley in European Journal of Heart Failure
- Vol. 5 (2) , 121-129
- https://doi.org/10.1016/s1388-9842(02)00254-4
Abstract
Background: Apoptosis may contribute to the myocardial dysfunction associated with heart failure (HF). Activation of the p38 MAPK cascade can induce apoptosis in non‐cardiac cells through increased ...Keywords
This publication has 18 references indexed in Scilit:
- p38 Mitogen-activated Protein Kinase Is Involved in Fas Ligand ExpressionJournal of Biological Chemistry, 1999
- Hypoxia-activated apoptosis of cardiac myocytes requires reoxygenation or a pH shift and is independent of p53Journal of Clinical Investigation, 1999
- Role for cyclin D1 in UVC-induced and p53-mediated apoptosisCell Death & Differentiation, 1999
- Fas‐induced DNA fragmentation and proteolysis of nuclear proteinsGenes to Cells, 1998
- Stretch-mediated release of angiotensin II induces myocyte apoptosis by activating p53 that enhances the local renin-angiotensin system and decreases the Bcl-2-to-Bax protein ratio in the cell.Journal of Clinical Investigation, 1998
- p53 and the hypoxia-induced apoptosis of cultured neonatal rat cardiac myocytes.Journal of Clinical Investigation, 1997
- Apoptosis in Myocytes in End-Stage Heart FailureNew England Journal of Medicine, 1996
- Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation.The Journal of cell biology, 1992
- Abnormal electrical properties of myocytes from chronically infarcted canine heart. Alterations in Vmax and the transient outward current.Circulation, 1992
- Immunoautoradiographic detection of proteins after electrophoretic transfer from gels to diazo-paper: analysis of adenovirus encoded proteins.Proceedings of the National Academy of Sciences, 1981