V. The Metabolism of Radioiodine and Radiation Dosage in Man

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Abstract
Metabolism of iodine in man is considered in relation to radiation dosage from radioactive iodine. The different isotopes of iodine are enumerated and their properties and uses mentioned. Radiation dosage to the thyroid gland and to the various tissues of the body is estimated, with special reference to I131 , I132 and I133 and attention is drawn to the relatively high dose given to the infant''s thyroid, high mainly because of the low gland mass. Alteration in radioiodine metabolism because of thyroid disease and of administration of drugs is discussed. The hazards of radioiodine and methods of protection are considered. It is suggested that iodine administration is the most useful method.