Efficient delivery of siRNA for inhibition of gene expression in postnatal mice
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- 29 July 2002
- journal article
- research article
- Published by Springer Nature in Nature Genetics
- Vol. 32 (1) , 107-108
- https://doi.org/10.1038/ng944
Abstract
It has recently been shown that RNA interference can be induced in cultured mammalian cells by delivery of short interfering RNAs (siRNAs). Here we describe a method for efficient in vivo delivery of siRNAs to organs of postnatal mice and demonstrate effective and specific inhibition of transgene expression in a variety of organs.Keywords
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