Reduction of Left Ventricular Hypertrophy After Exercise and Weight Loss in Overweight Patients With Mild Hypertension
Open Access
- 24 June 2002
- journal article
- clinical trial
- Published by American Medical Association (AMA) in Archives of internal medicine (1960)
- Vol. 162 (12) , 1333-1339
- https://doi.org/10.1001/archinte.162.12.1333
Abstract
HYPERTROPHY and concentric remodeling of the left ventricle are important manifestations of hypertension that are associated with an enhanced risk for morbidity and mortality. In the general population and in cohorts with hypertension or coronary artery disease, increased left ventricular mass is a predictor of cardiovascular events independent of blood pressure or other traditional risk factors.1-4 The geometric pattern of hypertrophy is also of prognostic importance. Patients with concentric remodeling, ie, an increase in the ratio of wall thickness to chamber dimension but normal left ventricular mass, have a cardiovascular risk intermediate between those with normal left ventricular structure and those with concentric hypertrophy.5,6 Regression of hypertrophy is associated with a reduction in cardiovascular risk.7-9This publication has 24 references indexed in Scilit:
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