Regulation of Drug and Bile Salt Transporters in Liver and Intestine
- 1 January 2003
- journal article
- review article
- Published by Taylor & Francis in Drug Metabolism Reviews
- Vol. 35 (4) , 305-317
- https://doi.org/10.1081/dmr-120026398
Abstract
Major determinants of the bioavailability of drugs are the degree of intestinal absorption and the hepatic first-pass effect. Drugs need to overcome several membrane barriers before reaching the sy...Keywords
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