Primary hemangiosarcoma of the spleen: Report of four cases

Publisher Website
Google Scholar
Abstract
Four cases of primary splenic hemangiosarcoma are described. The most common presenting symptoms were recurrent fever, malaise, and abdominal pain. Three patients also had complaints referable to the urinary tract. Severe hemo‐lytic anemia with bizarre or fragmented red blood cells on peripheral smear was noted in three patients, in two cases, for more than 1 year before diagnosis. Two patients had been treated for mammary carcinoma with ionizing radiation 10 years before developing hemangiosarcoma of the spleen. One patient had multiple congenital hemangiomas present from birth, and is thought to have developed hemangiosarcoma in a previously existing benign hemangi‐oma. None of our patients survived more than 7 months after the diagnosis of hemangiosarcoma. The importance of early detection and treatment of this tumor is discussed.