Studies on Formosan Soft Corals, II. Cytotoxic Cembranolides from the Soft Coral Lobophytum michaelae

1 October 1992

journal article
Published by American Chemical Society (ACS) in Journal of Natural Products

Vol. 55 (10) , 1430-1435
https://doi.org/10.1021/np50088a007

Abstract

Bioactivity-guided fractionation of a CHCl3 extract of the soft coral Lobophytum michaelae afforded a new cytotoxic cembranolide, lobomichaolide (1), and a known cytotoxic cembranolide, crassolide (2). The structure of 1 was determined by spectral and X-ray crystallographic analysis.

Keywords

SOFT CORALS
STRUCTURE
CEMBRANOLIDE
CYTOTOXIC
LOBOMICHAOLIDE
FORMOSAN
BIOACTIVITY
GUIDED

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