Type IV phosphodiesterase inhibition in experimental allergic encephalomyelitis of Lewis rats: Sequential gene expression analysis of cytokines, adhesion molecules and the inducible nitric oxide synthase
- 1 March 1999
- journal article
- Published by Elsevier in Journal of the Neurological Sciences
- Vol. 164 (1) , 13-23
- https://doi.org/10.1016/s0022-510x(99)00050-7
Abstract
No abstract availableKeywords
Funding Information
- Red Española de Esclerosis Múltiple
- INCLIVA Instituto de Investigación Sanitaria (0360/97, 1295/95)
This publication has 54 references indexed in Scilit:
- Suppression of IL-12 production by phosphodiesterase inhibition in murine endotoxemia is IL-10 independentEuropean Journal of Immunology, 1998
- Tumor necrosis factor blockade in actively induced experimental autoimmune encephalomyelitis prevents clinical disease despite activated T cell infiltration to the central nervous systemEuropean Journal of Immunology, 1997
- Critical Influences of the Cytokine Orchestration on the Outcome of Myelin Antigen‐Specific T‐Cell Autoimmunity in Experimental Autoimmune Encephalomyelitis and Multiple SclerosisImmunological Reviews, 1995
- Induction of nitric oxide synthase in demyelinating regions of multiple sclerosis brainsAnnals of Neurology, 1994
- Aminoguanidine, an inhibitor of inducible nitric oxide synthase, ameliorates experimental autoimmune encephalomyelitis in SJL mice.Journal of Clinical Investigation, 1994
- Encephalitogenic Th1 cells are inhibited by Th2 cells with related peptide specificity: Relative roles of interleukin (IL)-4 and IL-10Journal of Neuroimmunology, 1993
- A New Cyclic Nucleotide Phosphodiesterase Isozyme Expressed in the T-Lymphocyte Cell LinesBiochemical and Biophysical Research Communications, 1993
- Oral tolerance to myelin basic protein and natural recovery from experimental autoimmune encephalomyelitis are associated with downregulation of inflammatory cytokines and differential upregulation of transforming growth factor beta, interleukin 4, and prostaglandin E expression in the brain.The Journal of Experimental Medicine, 1992
- Effects of kainic acid on messenger RNA levels of IL-1β, IL-6, TNFα and LIF in the rat brainBiochemical and Biophysical Research Communications, 1991
- The adenylate cyclase-cAMP-protein kinase A pathway and regulation of the immune responseImmunology Today, 1988