HISTAMINE THERAPY IN ACUTE ISCHEMIA OF THE BRAIN
- 1 March 1950
- journal article
- other
- Published by American Medical Association (AMA) in Archives of Neurology & Psychiatry
- Vol. 63 (3) , 415-424
- https://doi.org/10.1001/archneurpsyc.1950.02310210061004
Abstract
EVALUATION of therapy in acute ischemia of the brain caused by arterial thrombosis, embolism and vascular insufficiency is sometimes difficult, since the incidence of spontaneous improvement can be rather high.1When a type of therapy produces consistent improvement, reduces the mortality and is readily available, simple to administer and safe to use, it merits consideration as a valuable addition to the therapeutic armamentarium. In my experience, such is the status of histamine therapy in acute ischemia of the brain. This preliminary report is made to stimulate further the evaluation of histamine therapy in this field. Whether the mechanism of ischemia of the brain is an intravascular thrombosis, a sudden vascular obstruction with reflex arterial spasm or a lowered blood pressure in a sclerotic but patent artery, the areas supplied by these vessels are in a state of anoxia.2Unless the original or collateral circulation is established early enough,Keywords
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