Familial Mediterranean Fever Successfully Treated With Etanercept
- 1 February 2007
- journal article
- case report
- Published by Wolters Kluwer Health in JCR: Journal of Clinical Rheumatology
- Vol. 13 (1) , 38-40
- https://doi.org/10.1097/01.rhu.0000255772.25658.7c
Abstract
Colchicine is the only drug known to effectively prevent familial Mediterranean fever (FMF) attacks, as well as FMF-associated amyloidosis. Unfortunately, colchicine is neither always effective nor always well tolerated, leaving some patients and their physicians with inadequate weaponry to fight this hazardous disease. We present a patient with recurrent episodes of abdominal, scrotal, and joint attacks, who was diagnosed with FMF and advised to take colchicine. Diarrhea prevented optimal treatment with this drug and led to a trial of etanercept, with resolution of FMF manifestations. This case adds to a growing body of evidence suggesting that tumor necrosis factor (TNF) blockade may result in resolution and prevention of further FMF attacks.Keywords
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