Vibrio cholerae expresses iron-regulated outer membrane proteins in vivo

Abstract
A comparison was made, using sodium dodecyl sulfate-polyacrylamide gel electrophoresis, of the outer membrane proteins of 4 strains of V. cholerae grown in vivo in infant rabbits and in vitro in low-Fe and Fe-supplemented defined media. In vivo-grown V. cholerae expressed novel outer membrane-associated proteins which, in part, were similar to those observed on V. cholerae grown in vitro under conditions of Fe deprivation. [The ability of microorganisms to acquire Fe is a virulence factor.].