Light chain heterogeneity of 19s and 7s anti‐γ‐globulins in rheumatoid arthritis and subacute bacterial endocarditis
- 1 May 1978
- journal article
- research article
- Published by Wiley in Arthritis & Rheumatism
- Vol. 21 (4) , 438-440
- https://doi.org/10.1002/art.1780210406
Abstract
Both 19S and 7S anti‐γ‐globulins in rheumatoid arthritis sera are enriched in kappa light chain bearing antibody molecules when compared to total 19S and 7S globulins from the same individuals. In patients with subacute bacterial endocarditis 19S anti‐γ‐globulins are also, to a degree, enriched in kappa light chains, whereas the 7S anti‐γ‐globulins have kappa to lambda light chain ratios indistinguishable from total 7S globulin.Keywords
This publication has 11 references indexed in Scilit:
- Circulating Immune Complexes in Infective EndocarditisNew England Journal of Medicine, 1976
- CHARACTERIZATION OF IgG COMPLEXES IN PATIENTS WITH RHEUMATOID ARTHRITIS*Annals of the New York Academy of Sciences, 1975
- SIMILARITIES IN THE LIGHT CHAINS OF ANTI-γ-GLOBULINS SHOWING CROSS-IDIOTYPIC SPECIFICITIESThe Journal of Experimental Medicine, 1974
- CROSS-IDIOTYPIC SPECIFICITY AMONG MONOCLONAL IGM PROTEINS WITH ANTI-γ-GLOBULIN ACTIVITYThe Journal of Experimental Medicine, 1973
- STUDIES ON HUMAN ANTIBODIESThe Journal of Experimental Medicine, 1968
- Studies on the Macroglobulins of Human Serum IV: The Frequency of Light Chain Types K and L in Polyclonal and Monoclonal γM.Scandinavian Journal of Haematology, 1967
- Exclusive Occurrence of k Chains in Isolated Cold HaemagglutininsScandinavian Journal of Haematology, 1965
- Variations in Affinities of Antibodies during the Immune Response*Biochemistry, 1964
- Antigenic heterogeneity of human Rh antibodies, rheumatoid factors, and cold agglutininsArchives of Biochemistry and Biophysics, 1964
- LOCALIZATION OF ANTIBODIES IN GROUP I AND GROUP II γ-GLOBULINSThe Journal of Experimental Medicine, 1963