New techniques in biosynthetic studies using 13C nuclear magnetic resonance spectroscopy. The biosynthesis of tenellin enriched from singly and doubly labelled precursors
- 1 January 1974
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications
- No. 8,p. 282-284
- https://doi.org/10.1039/c39740000282
Abstract
13 C n.m.r. spectroscopy was used for the dual purpose of assessing the relative merits of singly and doubly labelled precursors while establishing the biosynthesis of tenellin from 13C-labelled acetate, phenylalanine, and methionine; precursors in which two adjacent sites are labelled can provide superior information, and may prove useful for obtaining enrichment data at low incorporations.Keywords
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