ADVERSE-EFFECTS OF INTERFERON TREATMENT ON THE LIFE-SPAN OF NZB MICE

1 January 1979

journal article
research article

Vol. 31 (2) , 48-51

Abstract

NZB [New Zealand black] mice treated with interferon from birth and for over 1 yr, display some characteristics of an autoimmune disease similar to human systemic lupus erythematosus, hemolytic anemia and sjogren''s syndrome. In treated animals mortality is higher than in controls. Death occurs 3-6 mo. before that of mice injected with a mock preparation.

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