Colorimetric Determination of Maridomycin
- 1 April 1979
- journal article
- research article
- Published by Oxford University Press (OUP) in Agricultural and Biological Chemistry
- Vol. 43 (4) , 847-852
- https://doi.org/10.1080/00021369.1979.10863515
Abstract
A new, rapid and sensitive method for the quantitative determination of maridomycin (MDM) is proposed. The assay method is based on the reaction of the epoxy group of maridomycin with picric acid in ethyl acetate. This reaction product has absorption maxima at 415 and 475-480 nm in alkali. The absorbance at 490 nm, in a region where the interference from picric acid is negligible, follows Beer''s Law up to 1000 .mu.g of MDM/ml of sample solution. This reaction is not interfered with by the presence of other 16-membered macrolide antibiotics.This publication has 2 references indexed in Scilit:
- The reaction of picric acid with epoxides. II. The detection of epoxides in heated oilsJournal of Oil & Fat Industries, 1966
- The reaction of picric acid with epoxides I. A colorimetric methodJournal of Oil & Fat Industries, 1966