ANTIBODIES AGAINST VARIOUS TYPES OF SKELETAL MUSCLE FIBRES

  • 1 January 1965
    • journal article
    • research article
    • Vol. 9  (3) , 275-+
Abstract
Antibodies against skeletal muscle tissue may be directed against all muscle fibres ("overall" type) or against the distinct types of muscle fibres ("zebra" type). The antibodies of the "overall" type are frequently demonstrated in sera of patients with myasthenia gravis, rheumatoid arthritis, pernicious anaemia, Hashimoto''s disease and idiopathic adrenocortical atrophy. The antibodies of the " zebra" type are probably without a clinical significance. They can be divided into antibodies against the three distinct histochemical types of skeletal muscle fibres, namely into anti-red fibre, anti-white fibre and anti-medium fibre anti-bodies.