Branches on the α‐C Atom of Cyclosporin A Residue 3 Result in Direct Calcineurin Inhibition and Rapid Cyclophilin 18 Binding

This publication has 26 references indexed in Scilit:

• Substitution in Position 3 of Cyclosporin A Abolishes the Cyclophilin-mediated Gain-of-function Mechanism but Not Immunosuppression
  Published by Elsevier ,2004
• Two new cyclosporin folds observed in the structures of the immunosuppressant cyclosporin G and the formyl peptide receptor antagonist cyclosporin H at ultra-high resolution
  Organic & Biomolecular Chemistry, 2003
• Specific interaction between cyclophilin and cyclic peptides
  Biopolymers, 1995
• Peptidyl‐Prolyl cis/trans Isomerases and Their Effectors
  Angewandte Chemie International Edition in English, 1994
• The 3D structure of a cyclosporin analogue in water is nearly identical to the cyclophilin‐bound cyclosporin conformation
  FEBS Letters, 1994
• X-ray Structure of a Monomeric Cyclophilin A-Cyclosporin A Crystal Complex at 2·1 Å Resolution
  Journal of Molecular Biology, 1993
• Rusting of the Lock and Key Model for Protein-Ligand Binding
  Science, 1991
• Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes
  Cell, 1991
• Reinvestigation of the Conformation of Cyclosporin A in Chloroform
  Helvetica Chimica Acta, 1990
• Synthese von Cyclosporin und Analoga: Zusammenhang zwischen Struktur und immunsuppressiver Aktivität
  Angewandte Chemie, 1985