Escitalopram, the S-(+)-enantiomer of citalopram, is a selective serotonin reuptake inhibitor with potent effects in animal models predictive of antidepressant and anxiolytic activities
- 26 April 2003
- journal article
- research article
- Published by Springer Nature in Psychopharmacology
- Vol. 167 (4) , 353-362
- https://doi.org/10.1007/s00213-002-1364-z
Abstract
The pharmacological profile of escitalopram, the S-(+)-enantiomer of citalopram, was studied and compared with citalopram and the R-(−)-enantiomer, R-citalopram.Keywords
This publication has 31 references indexed in Scilit:
- Exploration of mice in a black and white test box: Validation as a model of anxietyPublished by Elsevier ,2002
- Do single enantiomers have something special to offer?Human Psychopharmacology: Clinical and Experimental, 2001
- Escitalopram (S-Enantiomer of Citalopram): Clinical Efficacy and Onset of Action Predicted from a Rat ModelBasic & Clinical Pharmacology & Toxicology, 2001
- Effect of Pindolol on the Function of Pre- and Postsynaptic 5-HT1A Receptors: In Vivo Microdialysis and Electrophysiological Studies in the Rat BrainNeuropsychopharmacology, 1996
- Current advances and trends in the treatment of depressionTrends in Pharmacological Sciences, 1994
- The pharmacological effect of citalopram resides in the (S)-(+)-enantiomerJournal Of Neural Transmission-Parkinsons Disease and Dementia Section, 1992
- Inhibition of shock-elicited ultrasonic vocalization by opioid peptides in the rat: A psychotropic effectPsychoneuroendocrinology, 1986
- Distress vocalization in rat pups a simple screening method for anxiolytic drugsJournal of Pharmacological Methods, 1985
- Effects of antidepressant drugs on histamine-H1 receptors in the brainLife Sciences, 1984
- Preliminary report of a simple animal behavior model for the anxiolytic effects of benzodiazepinesPharmacology Biochemistry and Behavior, 1980