TREATMENT OF HEMORRHAGIC GASTRITIS WITH CIMETIDINE

  • 1 January 1978
    • journal article
    • research article
    • Vol. 147  (5) , 737-739
Abstract
Patients [13] in whom bleeding from hemorrhagic gastritis was not controlled by a variety of therapeutic modalities were treated with cimetidine. Twelve of the 13 patients stopped bleeding. Three subsequently rebled, 2 of whom required an operation to control the bleeding. The average amount of blood transfused/patient before treatment with cimetidine was 16 units and after cimetidine, 1.6 units. Nine of the 13 patients died, but only 1 died of a hemorrhage. The remaining 8 patients died of a combination of sepsis and multiple organ failure. No adverse side-effects after the administration of cimetidine were observed. Cimetidine is a safe and reliable means to control bleeding from hemorrhagic gastritis. Once the diagnosis of hemorrhagic gastritis is established, treatment with cimetidine should be begun and continued until the underlying stress which initiated the bleeding is controlled.

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