Synthesis of Cleviolide and the Scobinolides
- 1 January 1993
- journal article
- letter
- Published by Georg Thieme Verlag KG in Synlett
- Vol. 1993 (07) , 463-465
- https://doi.org/10.1055/s-1993-22491
Abstract
The polyunsaturated 2(5H)-furanone natural products cleviolide (1) and (E)- and (Z)-scobinolide (2) and (3) have been efficiently synthesized in convergent fashion via palladiumcatalyzed coupling of 4-tributylstannyl-2(5H)-furanone (4) and 1-iodo-4-methylpent-3-en-1-yne (5).Keywords
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