The current status of the Salmonella problem, 10 years after publication of the report of the Committee on Salmonella of the National Research Council, was reviewed. The incidence of human salmonellosis has increased during this period. The major source of the Salmonella problem in man still derives from foods of animal origin, especially poultry, beef and pork. Contaminated products cause disease as the result of inadequate cooking or cross-contamination of working surfaces in the kitchen environment. The epidemiology of human salmonellosis has not changed during the past decade. Surveillance remains a powerful tool for protecting the consumer by discovering on-going epidemics, but it has done little to control the endemic problem from which epidemics emerge. Several outbreaks during the past decade indicate that the infecting dose, at least for certain Salmonella strains in certain foods, is considerably lower than that indicated on the basis of volunteer studies with adult male prisoners. The National ...