Cardiac sinus node dysfunction during lithium treatment

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Abstract
Li treatment has been associated with a wide range of cardiac complications. Three additional cases of cardiac sinus node dysfunction due to Li are reported. Two of the 3 cases were documented to be Li dependent by the use of Holter monitoring of cardiac rhythm. On the basis of this finding as well as other reports in the literature, careful monitoring of the pulse of patients taking Li as well as ECG monitoring of patients who are over the age of 50 or who have a history of cardiac disease is recommended. [The Li was being used in the treatment of unipolar and bipolar psychiatric illness.].

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