Absolute Quantitation of MDR1 Transcripts Using Heterologous DNA Standards—Validation of the Competitive RT-PCR (CRT-PCR) Approach
Open Access
- 1 June 1999
- journal article
- Published by Taylor & Francis in BioTechniques
- Vol. 26 (6) , 1114-1124
- https://doi.org/10.2144/99266st03
Abstract
The multidrug resistance (MDR1) gene product, P-glycoprotein (Pgp), is a 170-kDa ATP-dependent pump that expels a variety of anticancer drugs out of malignant cells, reducing drug accumulation and ...Keywords
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