STUDIES OF SINGLE MUSCLE FIBRES

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Abstract
The response of a single muscle fibre to induction shocks applied by microelectrodes has been studied. As stimulus strength is increased the length of fibre responding and the size of the response similarly increases. This parallelism continues longest when the electrodes are finest and most closely applied to the fibre but even then, after the contraction has spread a distance of about 1 mm., an all-or-nothing response of the entire fibre breaks through with further increase of stimulus intensity. This is in accord with an interpretation of the graded responses that more accurately defines the all-or-nothing phenomenon and which is developed in the text.