Cytogenetic and molecular studies in the Prader-Willi and Angelman syndromes: An overview
- 1 April 1993
- journal article
- review article
- Published by Wiley in American Journal of Medical Genetics
- Vol. 46 (1) , 2-6
- https://doi.org/10.1002/ajmg.1320460103
Abstract
The majority of patients with Angelman syndrome and Prader-Willi syndrome have a cytogenetic and molecular deletion of chromosome 15q11q13 with the primary difference being in the parental origin of deletion. Our current understanding of the cytogenetics and molecular genetics of these 2 clinically distinct syndromes will be discussed in this review.Keywords
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