Immunological identification and sequence characterization of a peptide derived from the processing of neuroendocrine protein 7B2
- 2 December 1991
- journal article
- Published by Wiley in FEBS Letters
- Vol. 294 (1-2) , 23-26
- https://doi.org/10.1016/0014-5793(91)81334-5
Abstract
A newly raised antiserum against the C‐terminal region of neuroendocrine protein 7B2 was used to purify a novel peptide from the culture media of the mouse corticotroph cell line AtT‐20. Based on partial sequencing, this peptide, which we call Cter‐7B2, begins at Ser156 and appears to result from the cleavage of pro7B2 after a five‐basic‐residue sequence. Thus, 7B2 processing may contribute to the diversity of peptides found in neuronal and endocrine cells.Keywords
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