Evidence for the existence of covalent nucleotide-thymidylate synthase complexes, identification of site of attachment, and enhancement by folates.
Open Access
- 1 September 1986
- journal article
- research article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 261 (27) , 12745-12749
- https://doi.org/10.1016/s0021-9258(18)67155-8
Abstract
No abstract availableThis publication has 20 references indexed in Scilit:
- Trapping and partial characterization of an adduct postulated to be the covalent catalytic ternary complex of thymidylate synthaseBiochemistry, 1986
- Studies on the polyglutamate specificity of thymidylate synthase from fetal pig liverBiochemistry, 1984
- Isolation of the covalent binary complex of 5-fluorodeoxyuridylate and thymidylate synthetase by trichloroacetic acid precipitationBiochemical and Biophysical Research Communications, 1984
- Fluorinated pyrimidines as tight-binding inhibitors of thymidylate synthetasePharmacology & Therapeutics, 1981
- Fluorine-19 nuclear magnetic resonance characterization of ternary complexes of folate derivatives, 5-fluorodeoxyuridylate and Lactobacillus casei thymidylate synthetaseBiochemistry, 1981
- Fluorine-19 nuclear magnetic resonance investigation of the noncovalent and covalent binary complexes of 5-fluorodeoxyuridylate and Lactobacillus casei thymidylate synthetaseBiochemistry, 1980
- Factors affecting substrate binding in Lactobacillus casei thymidylate synthetase as studied by equilibrium dialysisBiochemistry, 1976
- Effect of substrate analogs on the circular dichroic spectra of thymidylate synthetase from Lactobacillus caseiBiochemistry, 1975
- Mechanism of interaction of thymidylate synthetase with 5-fluorodeoxyuridylateBiochemistry, 1974
- Crystalline Dihydropteroylglutamic AcidNature, 1960