Oncogenic B-RAF Negatively Regulates the Tumor Suppressor LKB1 to Promote Melanoma Cell Proliferation
- 1 January 2009
- journal article
- research article
- Published by Elsevier in Molecular Cell
- Vol. 33 (2) , 237-247
- https://doi.org/10.1016/j.molcel.2008.12.026
Abstract
No abstract availableKeywords
Funding Information
- National Institutes of Health (CA102694, GM56203, K99CA133245, RO1 CA93947, UO1 CA84313)
- Charles A. King Trust
This publication has 62 references indexed in Scilit:
- AMPK Phosphorylation of Raptor Mediates a Metabolic CheckpointPublished by Elsevier ,2008
- LKB1 modulates lung cancer differentiation and metastasisNature, 2007
- Patterns of somatic mutation in human cancer genomesNature, 2007
- Regulation of epithelial tight junction assembly and disassembly by AMP-activated protein kinaseProceedings of the National Academy of Sciences, 2007
- AMPK and cell proliferation – AMPK as a therapeutic target for atherosclerosis and cancerThe Journal of Physiology, 2006
- BRAF mutation predicts sensitivity to MEK inhibitionNature, 2005
- The RAF proteins take centre stageNature Reviews Molecular Cell Biology, 2004
- AMP-activated protein kinase activators can inhibit the growth of prostate cancer cells by multiple mechanismsPublished by Elsevier ,2004
- A role for Drosophila LKB1 in anterior–posterior axis formation and epithelial polarityNature, 2003
- Mutations of the BRAF gene in human cancerNature, 2002