Bioactivation of S-(2,2-Dihalo-1,1-difluoroethyl)-l- cysteines and S-(Trihalovinyl)-l-cysteines by Cysteine S-Conjugate β-Lyase: Indications for Formation of both Thionoacylating Species and Thiiranes as Reactive Intermediates
- 1 January 1996
- journal article
- research article
- Published by American Chemical Society (ACS) in Chemical Research in Toxicology
- Vol. 9 (7) , 1092-1102
- https://doi.org/10.1021/tx960049b
Abstract
The covalent binding of reactive intermediates, formed by β-elimination of cysteine S-conjugates of halogenated alkenes, to nucleophiles was studied usinKeywords
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