Epinephrine-Induced Vacuole Formation in Parotid Gland Cells and Its Independence of the Secretory Process
- 1 January 1971
- journal article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 68 (1) , 121-123
- https://doi.org/10.1073/pnas.68.1.121
Abstract
Catecholamines cause rapid release of K(+) and formation of vacuoles in acinar gland cells. A high K(+) concentration in the medium bathing parotid gland slices prevents vacuole formation by epinephrine and facilitates the secretion of most of the exportable amylase. N(6)-monobutyryl 3':5'-cyclic AMP does not cause K(+) release and vacuole formation although it efficiently induces amylase secretion. It is suggested that the secretory process is independent of vacuole formation.Keywords
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