Bioactive Polymers 68-Controlled Release of Neomycine-Furazolidone Bicomponent System from Xanthan Hydrogel
- 1 January 1993
- journal article
- Published by SAGE Publications in Journal of Biomaterials Applications
- Vol. 7 (3) , 265-276
- https://doi.org/10.1177/088532829300700305
Abstract
The neomycine-furazolidone-xanthan complex has been synthesized. Neomycine is covalently linked to xanthan, while furazolidone is inserted in the hydrogel formed by the reaction between neomycine and xanthan. The content of neomycine and furazolidone depends on the drug rate in the reaction medium. Thus, a zero-order kinetics is obtained for the release of both neomycine and furazolidone in basic medium. The complex's antimicrobial activity is intensified.Keywords
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