Effects of Somatostatin, Glucagon and Insulin on Glycogen Synthesis in Isolated Rat Hepatocytes

Abstract
The effects of somatostatin on basal and hormonemediated rates of glycogenesis were studied in isolated rat hepatocytes. Somatostatin (1.5×10-11 - 1.5×10-8 M) had no effect on glycogen synthesis in the presence of 30 mM glucose and did not overcome a glucagon (1.5×10-10 M)-induced inhibition of glycogenesis.

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