Clinical features of ocular toxocariasis in Japan
- 1 January 2003
- journal article
- Published by Swets & Zeitlinger Publishers in Ocular Immunology and Inflammation
- Vol. 11 (4) , 269-275
- https://doi.org/10.1076/ocii.11.4.269.18266
Abstract
Purpose: To characterize the clinical features of ocular toxocariasis and to describe the unique aspects of the disease in Japan. Methods: Thirty-six cases diagnosed as ocular toxocariasis at the uveitis clinic of Tokyo Medical University Hospital were analyzed retrospectively. Results: Thirty-six cases comprised 34 adults (average age: 39 ± 10 years) and two nine-year-old boys. All cases were classified into two clinical types: posterior pole type (13 cases) and peripheral type (23 cases). Visual acuity was maintained over 20/20 in 50% and less than 20/200 in 14% of the cases. The peripheral type had worse outcomes than the posterior pole type in all of the endpoints examined: final visual outcome, frequency of ocular complications, and effectiveness of vitreous surgery. Antibody titers in intraocular fluids led to a diagnosis of ocular toxocariasis in eight seronegative cases of 33 cases examined for antibodies in both serum and intraocular fluid samples. Conclusions: The peripheral type had a worse prognosis than the posterior pole type. However, in general, ocular toxocariasis resulted in fair visual outcomes. The antibody titer in intraocular fluid was helpful in the diagnosis.Keywords
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