13C and 2H n.m.r. studies on the biosynthesis of O-methylasparvenone, a hexaketide metabolite of Aspergillus parvulus
- 1 January 1981
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications
- No. 5,p. 239-240
- https://doi.org/10.1039/c39810000239
Abstract
Incorporations of singly and doubly labelled 13C acetates and [2H3] acetate into O-methylasparvenone, a dihydronaphthalene metabolite of Aspergillus parvulus, and analysis of the resultant enriched samples by high-field 13C and 2H n.m.r. spectroscopy indicate a hexaketide biosynthesis and a novel acetate assembly pattern; the 2H-labelling pattern and levels of enrichment provide information on the sequence and mechanisms of the reduction, oxidation, and deoxygenation steps on the biosynthetic pathway.Keywords
This publication has 0 references indexed in Scilit: