Neurofibromatosis and Primary Hyperparathyroidism

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Abstract
Patients who have cutaneous and osseous neurofibromatosis, especially those with pathologic fractures, bone pain, roentgenographic evidence of cystic lesions, or hypercalcemia, should be evaluated carefully for the presence of a hormonally active parathyroid adenoma. They may have a reversible cause of osteitis fibrosa cystica. Palpation of the neck, serum and urine collections for measuring calcium and phosphorus levels, PTH determinations, bone roentgenograms, and bone biopsy help to establish the diagnosis.

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