Signal-mediated export of proteins from the malaria parasite to the host erythrocyte
Open Access
- 21 November 2005
- journal article
- review article
- Published by Rockefeller University Press in The Journal of cell biology
- Vol. 171 (4) , 587-592
- https://doi.org/10.1083/jcb.200508051
Abstract
Intracellular parasites from the genus Plasmodium reside and multiply in a variety of cells during their development. After invasion of human erythrocytes, asexual stages from the most virulent malaria parasite, P. falciparum, drastically change their host cell and export remodelling and virulence proteins. Recent data demonstrate that a specific NH2-terminal signal conserved across the genus Plasmodium plays a central role in this export process.Keywords
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