HMG CoA reductase inhibitors
- 1 February 1992
- journal article
- review article
- Published by Wolters Kluwer Health in Current Opinion in Lipidology
- Vol. 3 (1) , 22-28
- https://doi.org/10.1097/00041433-199202000-00005
Abstract
HMG CoA (β-hydroxy-β-methylglutaryl coenzyme A) reductase inhibitors are very effective in lowering total and low-density lipoprotein cholesterol. The incidence of adverse effects is very low with elevated transaminase levels and myopathy being of greatest concern. Administration of these drugs in combination with colestipol has produced a reduction in coronary artery stenosis and cardiovascular events.Keywords
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