Health-related quality of life burden of women with endometriosis: a literature review

Abstract
Purpose: The purpose of this study was to conduct a comprehensive and systematic literature review of the health-related quality of life (HRQL) burden of endometriosis in adults and adolescents.Methods: We conducted a systematic search and review of studies published between January 1999 and January 2006 using MEDLINE and relevant online resources. Search terms used included endometriosis, quality of life, burden of illness, psychology, and adolescent. We assessed: (1) the HRQL impact of endometriosis and related key symptoms; (2) the impact of specific pharmacologic and surgical treatments of endometriosis on HRQL; and (3) the presence and impact of endometriosis in adolescents.Results: Twenty relevant studies were identified and reviewed. Generic instruments most commonly used to assess HRQL in patients with endometriosis included the SF‐36 and the SF‐12. The EQ‐5D was used to measure utilities. The Endometriosis Health Profile-30 (EHP‐30) and its subset, the EHP‐5, have been recently developed ...

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