DIHYDROURACIL AS A GROWTH FACTOR FOR MUTANT STRAINS OF ESCHERICHIA COLI

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Abstract
A mutant strain of E. coli first characterized by growth response to dihydrouracil also grows on [beta]-ureidopropionic acid, [beta]-alanine, or pantothenic acid. Other mutant strains of E. coli originally described by their requirements for [beta]-alanine can also utilize dihydrouracil and [beta]-ureidopropionic acid. Dihydrouracil-2-C14 was scarcely converted to nucleic acid pyrimidines by the parent E. coli strain W and by a mutant strain that can utilize dihydrouracil for growth.